Recent Publications from the Diabetes Research Program

Dr. Bruce Verchere
Montane J, Bischoff L, Soukhatcheva G, Dai DL, Hardenberg G, Levings MK, Orban PC, Kieffer TJ, Tan R, Verchere CB.: Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets. J Clin Invest. 2011 Jul 1. pii: 43048. doi: 10.1172/JCI43048. [Epub ahead of print] PMID: 21737880
 
Dr. Bruce Verchere
Szabat M, Pourghaderi P, Soukhatcheva G, Verchere CB, Warnock GL, Piret JM, Johnson JD.: Kinetics and genomic profiling of adult human and mouse β-cell maturation. Islets. 2011 Jul 1;3(4). PMID: 21633187
 
Dr. Garth Warnock
Szabat M, Pourghaderi P, Soukhatcheva G, Verchere CB, Warnock GL, Piret JM, Johnson JD.: Kinetics and genomic profiling of adult human and mouse β-cell maturation. Islets. 2011 Jul 1;3(4). PMID: 21633187
 
Dr. Megan Levings
Patterson SJ, Han JM, Garcia R, Assi K, Gao T, O'Neill A, Newton AC, Levings MK.: Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells. J Immunol. 2011 May 15;186(10):5533-7. Epub 2011 Apr 15. PMID: 21498666
 
Dr. Jan Ehses
Ehses JA, Meier DT, Wueest S, Rytka J, Boller S, Wielinga PY, Schraenen A, Lemaire K, Debray S, Van Lommel L, Pospisilik JA, Tschopp O, Schultze SM, Malipiero U, Esterbauer H, Ellingsgaard H, Rütti S, Schuit FC, Lutz TA, Böni-Schnetzler M, Konrad D, Donath MY.: Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet. Diabetologia. 2010 Aug;53(8):1795-806. Epub 2010 Apr 21. PMID: 20407745
 
Dr. Brad Hoffman
Yang YH, Szabat M, Bragagnini C, Kott K, Helgason CD, Hoffman BG, Johnson JD.: Paracrine signalling loops in adult human and mouse pancreatic islets: netrins modulate beta cell apoptosis signalling via dependence receptors. Diabetologia. 2011 Apr;54(4):828-42. Epub 2011 Jan 7. PMID: 21212933
 
Dr. William Gibson
Ngai YF, Chijiwa C, Mercimek-Mahmutoglu S, Stewart L, Yong SL, Robinson WP, Gibson WT. Pseudohypoparathyroidism type 1a and the GNAS p.R231H mutation: Somatic mosaicism in a mother with two affected sons. Am J Med Genet A. 152A(11): 2784–90 (2010). PMID: 20979189
 
Dr. Dan Luciani
Luciani DS, Gwiazda KS, Yang TL, Kalynyak TB, Bychkivska Y, Frey MH, Jeffrey KD, Sampaio AV, Underhill TM, Johnson JD: Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death. Diabetes. 2009 Feb;58(2):422-32. PMID:19033399
 
Dr. Francis Lynn
Shimajiri Y, Kosaka Y, Scheel DW, Lynn FC, Kishimoto N, Wang J, Zhao S, German MS.: A mouse model for monitoring islet cell genesis and developing therapies for diabetes. Dis Model Mech. 2011 Mar;4(2):268-76. Epub 2010 Dec 6. PMID: 21135059