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Developmental Neurosciences
& Child Health


Early Human Experience Unit

The Early Human Experience Unit is a broadly based interdisciplinary unit that brings together a core group of investigators from a variety of disciplines. They pursue complementary research into how early experience affects biologic and behavioural development in infants, children, and youth. The integrative approaches extend from genetic and molecular levels to neural and behavioural systems, and include functional outcomes that reflect both basic process and social-environmental context in which the child lives. The research of the unit includes earliest experiences such as painful medical procedures in pre-term infants to end-of-life decisions in children with chronic terminal diseases.

Research projects and interests include:

  • Child development program
  • Learning and development program
  • Assessment of and interventions for preterm infant biobehavioural stress/pain responses
  • Healthy starts program
  • Adolescent health program
  • Transitions in pediatric palliative care
  • Optimized environments for infants
More details below.



Child development program

Ronald Barr

  • The effect of feeding, nutrients, and mother's voice on infant memory
  • Diurnal rhythms of soothing, taste response and cortisol in infants with and without colic
  • Developing a PDA (personal digital assistant) version of the "Baby's Day Diary"
  • The "Period of PURPLE Crying" Intervention Program to prevent shaken baby syndrome
Learning and development program
Ruth Grunau

  • Long-term effects of neonatal pain-related stress exposure in preterm infants
  • Etiology of developmental problems in attention, self-regulation, executive function, learning and cognition in preterm infants and children
  • Mother stress and caregiver-infant interaction
  • Pain reactivity in preterm and full term infants after NICU discharge
  • Pilot study on the role of magnetoencephalography in exploring mechanisms of learning problems
Developmental Care Program
Liisa Holsti

  • Developmental Care Program
  • Behavioural indicators of infant pain (BIIP): developing a new infant pain assessment
  • Comparing the accuracy and ease of use of an electronic diary with that of a paper/pencil form of the "Baby's Day Diary"
Healthy starts program
Tim Oberlander

  • Behaviour and development in infants with prenatal psychotropic exposure
  • Biobehavioural neural gradients in child development and community context
  • Pain in children with development disabilities
Adolescent health program
Elizabeth Saewyc

  • Health disparities of lesbian, gay, and bisexual teens
  • Survey of street-involved youth throughout BC
  • Randomized clinical trial of a brief intervention to reduce problem drinking
  • Enacted stigma, gender, and risk behaviours of school youth
  • Sexually exploited very young teens
  • ON-TRAC: tracking transitions to adult care for youths with special health care needs
Transitions in pediatric palliative care
Hal Siden

  • New Emerging Team: framework to study pediatric palliative care for children and families from the biomedical/clinical development and health services utilization perspectives
  • Biomarkers for pain, imaging pain, understanding pain sources and treatment in non-verbal children
  • Creating evidence base for improved policy and practice and user-system access to resources via electronic collaboration
Optimized environments for infants
Fay Warnock

  • Identifying typical and atypical patterning in the composite indicators of infant pain and stress reactivity
  • Clarifying and optimizing the regulative role of maternal care-giving on infant pain and stress reactivity within the context of infant prenatal and postnatal exposures to antidepressant medications, maternal depression and complex health care environments

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Last updated: 06/28/2010

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